Webinar 2: Learning from Learning Health Systems Around the Globe

About the speakers

Ana Morales is an Associate Professor in the Geisinger Department of Genomic Health, a board-certified genetic counselor, and an implementation scientist focused on translating evidence-based genomic care into routine clinical practice. Her work centers on designing, implementing, and evaluating scalable strategies to improve the delivery of genetic services across health systems. She serves as Principal Investigator of the IMPACT-FH study, which investigates implementation science-based approaches to increase the identification of individuals with familial hypercholesterolemia (FH) while promoting cascade genetic testing in primary care. In addition, she serves as a co-investigator of the CARE-FH study, which evaluates the sustainability of a newly implemented FH screening initiative. Ana is a co-author of the 2026 National Lipid Association Expert Consensus Statement on Familial Hypercholesterolemia, reflecting her commitment to advancing evidence-based approaches for FH identification, genetic evaluation, and family-based care.

Peter Margolis, MD, PhD, is Adjunct Professor of Pediatrics at Stanford University School of Medicine, Emeritus Professor of Pediatrics at the University of Cincinnati School of Medicine, and former Co-Director of the James M. Anderson Center for Health Systems Excellence at Cincinnati Children’s Hospital Medical Center. His work encompasses the application and study of systems improvement methods across a broad range of areas, including primary and sub-specialty care, communities, and public health settings to improve the health outcomes of children, families, and communities.

Over the last 20 years, he and his research team have developed innovative approaches that engage patients, their families, clinicians, scientists, and communities in developing network-based learning health systems that simultaneously improve care, spawn innovation, and accelerate research. This work has repeatedly demonstrated significant impact on the process and outcomes of care.

Dr. Margolis was co-PI of an NIH Transformative Research Grant focused on developing learning health systems for children with chronic illness by harnessing the inherent motivation and expertise of all stakeholders involved.

Dr. Margolis has extensive experience in large-scale comparative effectiveness research, the creation of large-scale interoperable data systems, managing large project teams, and engaging individuals from diverse backgrounds to co-produce improved care and research. He served as Chair of the PCORnet Council, guiding the Patient-Centered Outcomes Research Institute’s investment in transforming research infrastructure in the US. The ImproveCareNow Network, which he founded, was awarded the Drucker Prize, the largest non-profit management and innovation award in the US. Dr. Margolis is an elected member of the National Academy of Medicine.

Céline Mötteli-Graf is a PhD candidate in the Care and Rehabilitation Sciences programme at the University of Zurich and part of the Swiss Learning Health System cohort. With a background in physiotherapy and several years of clinical experience in musculoskeletal rehabilitation, her research focuses on health services and implementation research in non-communicable diseases. Her PhD investigates the management of knee osteoarthritis in Switzerland, addressing evidence-performance gaps and the alignment of care with clinical guidelines. Her work includes analysing patient care pathways, engaging stakeholders through structured dialogue, developing policy recommendations, and exploring contextual factors that influence guideline implementation. She is particularly interested in strengthening evidence-based conservative care and bridging the gap between research, clinical practice, and health policy to improve healthcare delivery and patient outcomes.

Sue Lacey Bryant - Passionate about bringing knowledge to bear on decision-making to improve clinical outcomes, staff and patient experience, and productivity, Sue Lacey Bryant is Visiting Professor in Knowledge and Information Mobilisation at Manchester Metropolitan University. She convenes regular transatlantic roundtables debating hot topics.
Formerly Chief Knowledge Officer for NHS England, Sue is an Honorary Advisor to Health Innovation Network, Kent, Surrey Sussex with particular interests in Knowledge Mobilisation, Learning Health Systems (LHS) and AI. Also a KM adviser and consultant, a coach and mentor, Sue is a Leading Practitioner of FedIP and immediate past President of CILIP.
Widely published, Sue's recent publications include Actioning Actionable Knowledge, and Hand in Glove: Health Equity and LHS. Upcoming publications include contributions to books on leadership, and a chapter on AI and LHS in primary care.